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Prolonged Therapeutic Hypothermia After Traumatic Brain Injury in Adults JAMA 289:2992-2999,3007, McIntyre,L.A.,et al, 2003 See this aricle in Pubmed Article Abstract Therapeutic hypothermia may reduce the risk of mortality and poor neurologic outcome in adults with TBI. Outcomes were influenced, however, by depth and duration of hypothermia as well as rate of rewarming (

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